Virtual Conference
Dementia Conference

Aline Kegler

Federal University of Santa Maria, Brazil

Title: The cognitive dysfunction in epilepsy patients


Epilepsy is a brain disease that affects around 50 million people worldwide. It is characterized by recurrent seizures, which are brief episodes of involuntary movement that may involve a part (partial) or entire body (generalized) and are sometimes accompanied by loss of consciousness and control of bowel or bladder function. Some epilepsy patients may be at a higher risk of developing dementia, while individuals with some forms of dementia, particularly Alzheimer’s disease and vascular dementia, are at significantly higher risk of developing epilepsy. Consistent with this emerging view, epidemiological findings reveal that epilepsy and Alzheimer’s disease share common risk factors. In the present study, a neuropsychological evaluation (battery of cognitive tests) was held with two groups: epilepsy and control group. The results demonstrated a worse performance related to cognitive impairment, including praxis, perception, attention, language, executive functions, long-term semantic memory, short-term visual memory, and total memory in epilepsy group when compared to control group. Furthermore, inflammatory biomarkers (TNF-?, IL-1? and IL-6) are also increase in epilepsy group (blood sample) suggesting correlation to its damage. This study supports the evidence of a distinct neuropsychological profile in epilepsy patients. Furthermore, our results suggests a link between inflammatory and cognitive dysfunction in patients with epilepsy


Completed doctoral studies at Federal University of SantaMaria-Brazil. Neurological disorders, biochemistry, neurology and pharmacology are the fields of research.Some articles published at respected journals such as Gene, Biomed Research International, Progress in Neuropsychopharmacology & Biological Psychiatry. Oral presentation at the 1 st Congress of The European Academy of Neurology, Berlin-DE. Speaker at Geriatrics Congress and Alzheimer (2021). Guest speaker at 27th International Conference on Neurology: Neurochemistry, Neuropharmacology and Neurosciences (Canada, March 2022)