
Daniel Oliveira Zago
Hospital Premium, BrazilTitle: Pallidotomy Associated to Thalamotomy for Parkinson’s Disease Treatment: Case report
Abstract
Parkinson’s
disease (PD) is a chronic and progressive neurodegenerative disease, standing
as the second most prevalent neurodegenerative
disease in the world. Ten to fifty new cases per 100.000 people are diagnosed
every year, being the male elderly the most
affected by it. Case Presentation: A male patient, 63 years old, diagnosed with
PD, presenting severe tremor, mainly in the
left limbs,
rigidity and mild bradykinesia, refractory to drug therapy. Nine years after
the diagnosis, he
underwent surgery for a thalamotomy, aimed at the Right Ventral Intermediate
Nucleus (Vim), with full motor sympthomatology recovery. Nine years after this
ablative procedure, in 2017, the patient presented with hypomimia, hypophonia,
muscular rigidity, bradikynesia and resting tremor. Due to the return of the
motor symptoms, the patient underwent another surgery. This time, a posteroventral
pallidotomy was the chosen ablative surgey. After the surgery, a significant
motor symptomology reduction was noticed, mainly in the left limbs. Discussion:
A bibliographic study about PD’s history, the circuitry involved in its
physiopathology and its treatment,
mainly surgical, was carried out. A cost-benefit analysis regarding Brazil’s
public healthcare system, the country’s social and economic reality how it
influences on whether Deep-brain-stimulation or ablative surgery should
be the treatment of choice for the case was also . Conclusion: Ablative surgery
should remain as a therapeutic option for PD due to its safety, low
cost, and high effectiveness to improve PD’s motor symptoms.
Biography
Daniel Zago is a physician who recently
graduated from Pontificial Catholic University of Goiás, certified ACLS and BLS
by the American Heart Association and has a wide range of research areas. He
now works as a ER doctor at Saint Helen’s Hospital in Goiás.